Steroid-induced osteoporosis: how can it be avoided?
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چکیده
منابع مشابه
Steroid-induced osteoporosis: how can it be avoided?
In 1932, Harvey Cushing wrote: ‘The greatly compressed bodies of the vertebrae ... were so soft they could easily be cut with a knife’. Today, steroid-induced osteoporosis is still of major clinical relevance. Glucocorticosteroids induce a biphasic bone loss with a rapid initial phase of ;10–15% during the first few months and a slower phase of ;2–5% annually. As shown in Figure 1, steroids do ...
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متن کاملHow to prevent steroid induced osteoporosis.
The first choice for prevention of corticosteroid osteoporosis is a potent oral bisphosphonate-for example, alendronate or risedronate. Intravenous bisphosphonates should be considered for patients intolerant of the oral route. For patients receiving chronic low dose corticosteroids treatment with calcium and vitamin D may prevent further bone loss. Use of parathyroid hormone is promising.
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ژورنال
عنوان ژورنال: Nephrology Dialysis Transplantation
سال: 2003
ISSN: 0931-0509,1460-2385
DOI: 10.1093/ndt/gfg067